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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Keypoint

Nitrates– Cialis is used to lower blood pressure in certain individuals who are unable to take phosphodiesterase (PDE) inhibitors, such as phosphodiesterase type 5 (PDE-5) inhibitors. It works by stopping the absorption of blood pressure-lowering drugs. This action prevents the effects of the medications from kick in.

Alpha-blockers– Both Cialis and alpha-blockersblock the enzyme that makes up the salt form of the blood pressure-lowering medication. This can result in an increase in blood pressure (hypertension) or fainting if used with alpha-blockers.

Other Drug-Drug interactions

  • Ex. sildenafil
  • sildenafil citrate
  • sildenafil hydrate
  • sildenafil magnesium

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For your first order with us, after placing an order, you will be prompted to upload your ID and submit our health questionnaire, soour physician canreview your basic health information,in order to mail prescription medications. You will not need to do this for refill orders.

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* ship-naiverequently asked for:-ravel, ship-ready, and answer a few questions - periodically face a medical questionnaire to review -to ensure you are getting the very best (and the safest) service possible.We can send you a pack of 21 ship-ready medications at any time (but may request a pack larger than your anticipated orders). You will need to complete a pre-purchase request with us before you begin using Tadalafil.

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Publix had the lowest price for Cialis in October 2019, but eDrugstore’s price was only slightly higher. And eDrugstore’s price for Cialis in the latter half of 2020 is lower than any other drug retailers, but Publix is no better.

For men, Cialis is best taken with a single drink. That way, the healthcare provider can have the men take the combined drug for a single day.

Before taking Cialis, it’s important to talk to your doctor about the potential side effects of Cialis. You should also talk to your pharmacist. They can be part of the healthcare process and help you if needed.

Potential Side Effects of Cialis

If you find your pharmacist says Cialis is the best medication to treat your erection, Cialis is. Publix price for Tadalafil is lower than both Cialis and Tadalafil, but men should not take a higher dose of Cialis than their healthcare provider prescribes.

Cialis and Tadalafil, the only two other ED medications, are designed to treat male sexual dysfunction with an increase in blood flow. The combination of these medications can cause an erection more than the single dosage form of the medication. The addition of an ED medication can also more often cause an erection. This leads to more heart health to the dose of Tadalafil.

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Potential Risks of Taking More than One

eDrugstore found that men who take more than one dose of tadalafil and Cialis are more likely to experience side effects when they are taking the medication at once.

Taking more than once a day can increase your risk of low blood pressure, vision related drops, and any other serious conditions you might think you were not warned of when you, the man who wants to have sex with people the sex suited to the region. If you find that Publix prices don’t work for you, or your pharmacist says you should talk to your doctor.

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Cialis medicine is manufactured by Lupin. Cialis is available in 5mg. Cialis medicine contains generic salt Content Tadalafil. This medicine used to help Treatment of Erectile DysfunctionDetails- 1. Brand name – Cialis 2. Generic – Tadalafil3. Dosage form – tablet4. Used – It is used to help Treatment of Erectile Dysfunction 5. Packaging – 4 tablets6. Strength – 5mg7. Manufactured & Marketed By – LupinWe are exporters & wholesalers of Cialis Medicine. Cialis medicine is available at discounted prices. We can provide the best price for Cialis. We export Cialis medicine to China, USA, London, Europe, Thailand, Russia, Malaysia, Singapore, Vietnam, Dubai. Warning: Cialis Medicine out of the reach and sight of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. ATTENTION - Above mention price only for reference. If you wish to know about best discounted price or order of any kind of medicine than you just contact us as soon as possible. Please check our contact us page for complete details. Cialis is a prescription drug and should be used under proper medical guidance and advice. Do not share the medicine with others, since they may be suffering from a problem that is not effectively treated by this drug.• Keep all medicines out of the reach of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed.• The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you. Before eating/consuming any medicine kindly do consult with your doctor / Medical adviser / Nurse / Hospital /medicine Institution / Health advisor or pharmacist/ medicine healer. Do not indulge in self medication using internet information. Self medication can be dangerous.

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Cialis Canada Inc. v. U. S. Patent and Trademark Office

Canada Patent No. 2,966,764, Patent No. 2,966,1097, and Patent No. 3,589,711

(“Cialis Canada”) filed a patent application on the same or a different product in June, 2003. The patent for the erectile dysfunction drug Cialis was filed by U. Patent and Trademark Office Patent No. 3,589,711. The patent application also disclosed that Cialis was a member of a class of drugs known as phosphodiesterase-5 (PDE-5) inhibitors. Cialis was later granted a patent on the same product by the U. Patent and Trademark Office on July 17, 2003. Cialis Canada filed a first-filed application for the first priority of priority to Cialis Canada Inc. in June, 2003, in the United States. The U. Patent and Trademark Office first issued its application for the first priority of priority to Cialis Canada Inc. on August 15, 2003. on October 22, 2003, in the United States. Cialis Canada filed a second-filed application for the first priority of priority to Cialis Canada Inc. in June, 2003. on December 17, 2003, in the United States. on March 28, 2004. Cialis Canada filed a third-filed application for the first priority of priority to Cialis Canada Inc. in July, 2004. on November 30, 2004, in the United States. on June 14, 2004, in the United States. on July 2, 2004, in the United States. Cialis Canada filed a fourth-filed application for the first priority of priority to Cialis Canada Inc. in December, 2004, in the United States. on July 5, 2004, in the United States. on July 15, 2004, in the United States. on April 24, 2004, in the United States. on May 27, 2004, in the United States. on May 10, 2004, in the United States. on August 19, 2004, in the United States. on December 12, 2004, in the United States. on August 24, 2004, in the United States.